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Question #47682

Difficulty: 8/10 | 🟢 Free

The Question

Read the following statements regarding a bioactive molecule routinely administered to patients following a renal allograft: I. It is commercially produced via the fermentation activity of the fungus Trichoderma polysporum. II. It primarily suppresses the humoral immune response to prevent antibody-mediated destruction of the graft. III. Its prolonged administration paradoxically increases the patient's susceptibility to opportunistic pathogens. IV. It acts by inhibiting the activation of T-lymphocytes, thereby dampening cell-mediated immunity. Which of the above statements are CORRECT?

Options

  • A.

    I, III, and IV

  • B.

    I, II, and III

  • C.

    I and IV only

  • D.

    II, III, and IV

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Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Evolutionary_Exception

Tackle problems where standard rules evolve or change based on specific environmental constraints.

Concepts Behind This Question

Endomycorrhiza|Habitat_Fragmentation|Biodiversity

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Students often memorize 'immunosuppressant' without linking it to the specific branch of the immune system (Cell-Mediated Immunity via T-cells) responsible for allograft rejection.

The trap lies in Statement II, which incorrectly attributes graft rejection prevention to the suppression of humoral (B-cell/antibody) immunity.

Quick Facts About This Question

Question Information

SubjectBiology
ChapterMicrobes in Human Welfare - Class 12
ConceptMycorrhiza Nutrient Dynamics
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree