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Question #47577

Difficulty: 8/10 | 🟢 Free

The Question

During gametogenesis, the fidelity of DNA replication and the precision of homologous recombination are critical. Consider a scenario where recombination during Prophase I encounters highly repetitive satellite DNA, leading to unequal crossing over. Which of the following statements regarding this process and its genetic consequences is INCORRECT?

Options

  • A.

    The enzyme-mediated crossing over during the pachytene stage can result in copy number variations if homologous chromosomes misalign at repetitive satellite DNA sequences.

  • B.

    Satellite DNA sequences form a major bulk of the human genome and code for essential recombinase enzymes, making their unequal crossing over highly deleterious to meiotic progression.

  • C.

    If replication slippage occurs at these repetitive sequences during the preceding S phase, resulting point mutations in coding regions may be buffered by the degeneracy of the genetic code.

  • D.

    The synaptonemal complex formed during zygotene stabilizes paired chromosomes, but non-allelic homologous recombination at satellite regions can still cause structural chromosomal aberrations.

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Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Comparative_Analysis

Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.

Concepts Behind This Question

Pachytene|Genetic Code Degeneracy|Okazaki Fragment Logic

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Students often confuse the high structural and diagnostic importance of Satellite DNA (used in DNA fingerprinting) with functional coding capacity.

The trap relies on the direct NCERT line stating 'satellite DNA normally does not code for any protein'.

Failing to recall this makes Option B seem plausible because recombinase is indeed an essential enzyme for meiotic progression.

Quick Facts About This Question

Question Information

SubjectBiology
ChapterCell Cycle and Cell Division - Class 11
ConceptProphase I Sub-stages Sequence
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree