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Question #47497
The Question
Certain enveloped viruses hijack the host cell's endolysosomal pathway, relying on the acidic environment of the lysosomes for viral uncoating or capsid maturation. If a host cell is treated with a specific pharmacological inhibitor of vacuolar -ATPases (V-ATPases), disrupting lysosomal pH homeostasis, all of the following physiological consequences will occur, EXCEPT:
Options
- A.
The viral genetic material will remain trapped within the endolysosomal compartment, halting the infection cycle.
- B.
Host lysosomal acid hydrolases, such as lipases and proteases, will fail to achieve their optimal catalytic activity.
- C.
The structural budding and packaging of primary lysosomes from the trans-face of the Golgi apparatus will be completely arrested.
- D.
The pH-dependent conformational changes required for viral envelope fusion or capsid maturation will be inhibited.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Evolutionary_Exception
Tackle problems where standard rules evolve or change based on specific environmental constraints.
Concepts Behind This Question
Bacteriophage Genetic Material|Archaebacteria Cell Wall Composition|Adaptive Radiation Logic
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Distinguishing between the 'structural biogenesis' of an organelle and its 'functional maturation'.
Students often fall for the trap of assuming that inhibiting an organelle's biochemical function (acidification via proton pumps) will retroactively prevent its physical formation (packaging at the Golgi apparatus).
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Biological Classification - Class 11 |
| Concept | Bacteriophage Genetic Material |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |