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Question #47492

Difficulty: 8/10 | 🟢 Free

The Question

Viroids are infectious, low molecular weight, naked RNA molecules. During their replication inside a eukaryotic host, they produce multimeric RNA transcripts that must be cleaved into unit-length circular genomes. Which of the following accurately distinguishes this viroid RNA cleavage from the post-transcriptional processing of the host's heterogeneous nuclear RNA (hnRNA)?

Options

  • A.

    Viroid RNA cleavage is mediated by the host's snRNPs, whereas hnRNA processing relies on the host's RNA polymerase II.

  • B.

    Viroid RNA undergoes autocatalytic cleavage via its own intrinsic ribozyme activity, whereas host hnRNA is cleaved and ligated by the spliceosomal complex.

  • C.

    Both viroid RNA and host hnRNA rely entirely on the host's spliceosome for the removal of non-coding repetitive sequences.

  • D.

    Viroid RNA is cleaved by host-derived trans-acting ribozymes, whereas host hnRNA undergoes autocatalytic self-splicing without protein assistance.

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Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Regulatory_Failure

Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.

Concepts Behind This Question

Sulfur-35|Phosphorus-32|Obligate_Intracellular_Parasitism

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Students often conflate all RNA-based catalytic cleavage in eukaryotes with the spliceosome machinery.

The trap lies in failing to distinguish between the intrinsic, autocatalytic ribozyme activity of a viroid (self-sufficiency in cleavage) and the complex-dependent (snRNP-mediated) splicing of host primary transcripts (hnRNA).

Quick Facts About This Question

Question Information

SubjectBiology
ChapterBiological Classification - Class 11
ConceptViroid vs Virus Distinction
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree