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Question #47480
The Question
A novel genetically modified protein, approved by GEAC, is deployed as an antifungal agent targeting the cell wall of pathogenic Ascomycetes. Regarding the biochemical nature of this target and the intervention, which of the following statements is INCORRECT?
Options
- A.
The targeted fungal cell wall primarily consists of a homopolymer of N-acetylglucosamine (NAG) and beta-glucans.
- B.
The GEAC-approved protein must specifically bind to beta-1,4 glycosidic linkages, as human amylases are restricted to hydrolyzing alpha-1,4 linkages.
- C.
Standard antibacterial lysozymes are highly effective against these fungi because they readily cleave the beta-1,4 glycosidic bonds shared by both chitin and bacterial peptidoglycan.
- D.
The structural integrity of the targeted Ascomycetes relies on a chitin-glucan complex, making it a highly specific target that minimizes toxicity to human host cells.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Ascomycetes Sac Fungi|GEAC Oversight|Antibody Structure Logic
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: The misconception that sharing the same bond type (beta-1,4 glycosidic linkage) makes two different macromolecules susceptible to the same enzyme.
Students often memorize 'lysozyme breaks beta-1,4 bonds' and 'chitin has beta-1,4 bonds' and erroneously conclude lysozyme is a potent antifungal.
This tests deep understanding of enzyme active site specificity (lock and key) and the distinction between homopolymers (chitin) and heteropolymers (peptidoglycan).
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Biological Classification - Class 11 |
| Concept | Ascomycetes Sac Fungi |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |