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Question #47473
The Question
During embryonic development, a genetic mutation disrupts the differentiation of specific neurosecretory stem cells, preventing them from establishing axonal terminals at the primary capillary plexus of the hypophyseal portal system. Which of the following physiological consequences will be directly observed in the adult organism?
Options
- A.
Complete inability to release oxytocin and vasopressin into the systemic circulation.
- B.
Failure of the pars distalis to secrete gonadotropins due to the absence of GnRH in the portal circulation.
- C.
Hypersecretion of all anterior pituitary hormones due to the loss of direct neural inhibition.
- D.
Atrophy of the pars nervosa due to the absence of trophic releasing hormones from the hypothalamus.
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Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Evolutionary_Exception
Tackle problems where standard rules evolve or change based on specific environmental constraints.
Concepts Behind This Question
Neurotransmitter Receptor Specificity|Hypothalamic-Pituitary Axis Integration|Differentiation of Stem Cells
Why This Question Is Tricky
Common Mistakes
The Conceptual Pivot lies in distinguishing the anatomical pathways of hypothalamic integration.
A common misconception is conflating the 'direct axonal transport' of ADH/Oxytocin to the posterior pituitary with the 'axonal release' of releasing hormones (like GnRH) into the portal system's primary capillary plexus.
By specifying the 'primary capillary plexus', the question strictly isolates the anterior pituitary's regulatory pathway, testing the student's precise spatial and functional understanding of the Hypothalamic-Pituitary axis.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Neural Control and Coordination - Class 11 |
| Concept | Neurotransmitter Receptor Specificity |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |