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Question #47435
The Question
A specific neurotoxin selectively disrupts the microtubule-dependent anterograde axonal transport in the neurons originating from the supraoptic and paraventricular nuclei of the hypothalamus. Which of the following represents the most accurate physiological consequence of this disruption?
Options
- A.
Synthesis of neurohormones within the pars nervosa will immediately cease, leading to diabetes insipidus.
- B.
Secretory vesicles will accumulate in the hypothalamic cell bodies, resulting in impaired facultative water reabsorption and weak uterine contractions.
- C.
The release of gonadotropin-releasing hormone (GnRH) into the hypophyseal portal system will be blocked, causing hypogonadism.
- D.
The synaptic delay at the neuro-neuronal junctions within the posterior pituitary will increase, slowing down oxytocin release.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Comparative_Analysis
Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.
Concepts Behind This Question
Synaptic Delay Determinant|Adenohypophysis vs Neurohypophysis Origin|Hypothalamic-Hypophyseal Portal System
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Distinguishing between the direct neural axonal transport to the Neurohypophysis versus the vascular portal transport to the Adenohypophysis.
The trap relies on students confusing the site of synthesis (Hypothalamus) with the site of release (Posterior Pituitary), and misidentifying the posterior pituitary as having neuro-neuronal synapses rather than being a neuro-hemal storage organ.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Neural Control and Coordination - Class 11 |
| Concept | Synaptic Delay Determinant |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |