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Question #46897
The Question
The Hamburger phenomenon (chloride shift) is essential for the transport of carbon dioxide as bicarbonate. If a chemical inhibitor completely blocks the Band 3 anion exchanger proteins on the erythrocyte membrane at the systemic capillary level, which of the following physiological consequences will occur?
Options
- A.
The chloride ion concentration in the venous blood plasma will become significantly lower than in the arterial blood plasma.
- B.
The continuous hydration of CO2 within the erythrocytes will be severely impaired due to the intracellular accumulation of bicarbonate.
- C.
The intracellular pH of the erythrocytes will rise drastically due to the retention of alkaline bicarbonate ions.
- D.
The oxyhemoglobin dissociation curve will shift to the left due to the subsequent accumulation of CO2 in the peripheral tissues.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Metabolism vs. In-vitro Reactions|Chloride Shift (Hamburger Phenomenon)|Respiratory Volume vs. Capacity
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often memorize the chloride shift mechanically ('Cl- goes in, HCO3- goes out') without understanding its thermodynamic purpose.
The shift prevents product inhibition of Carbonic Anhydrase.
The question also tests the 'Normal vs.
Inhibited' trap in Option A, where students might reflexively choose the normal physiological event rather than the consequence of the inhibition.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | The Living World - Class 11 |
| Concept | Metabolism vs. In-vitro Reactions |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |