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Question #46849
The Question
A researcher administers a highly specific ATPase inhibitor to the gastric mucosa of an experimental vertebrate model. Based on the principles of glandular secretion and digestive enzyme specificity, which of the following statements regarding the subsequent physiological consequences is INCORRECT?
Options
- A.
The optimal acidic micro-environment (pH ~1.8) required for the autocatalytic cleavage of pepsinogen will not be established.
- B.
The chief cells will halt the synthesis and secretion of pepsinogen due to the disruption of the positive feedback loop mediated by active pepsin.
- C.
The hydrolysis of complex dietary proteins into proteoses and peptones within the gastric lumen will be severely compromised.
- D.
The catalytic activity of salivary amylase within the swallowed bolus will persist for a longer duration in the gastric cavity.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Comparative_Analysis
Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.
Concepts Behind This Question
Glandular Secretion Mechanism|Frog Digestive Enzyme Specificity|Enzyme Denaturation
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Differentiating between the luminal 'activation' of a proenzyme (which is pH-dependent and autocatalytic) and the cellular 'secretion' of that proenzyme (which is neurally/hormonally mediated).
Students often fall into the trap of assuming that blocking a downstream luminal reaction automatically halts upstream glandular exocytosis via feedback inhibition.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Structural Organisation in Animals - Class 11 |
| Concept | Glandular Secretion Mechanism |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |