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Question #46773
The Question
A eukaryotic cell possesses a mutation that reduces DNA polymerase processivity specifically when navigating through highly condensed chromatin regions. This leads to severe replication-transcription conflicts. To resolve these structural stallings, the cell diverts massive amounts of its metabolic energy (ATP) toward DNA repair mechanisms. Consequently, which of the following processes in protein synthesis will be most directly and immediately bottlenecked due to this specific energy depletion?
Options
- A.
Formation of the peptide bond between adjacent amino acids by peptidyl transferase
- B.
Translocation of the ribosome along the mRNA in the 5' to 3' direction
- C.
Activation of amino acids and their linkage to cognate tRNAs
- D.
Association of the larger ribosomal subunit with the initiation complex
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Comparative_Analysis
Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.
Concepts Behind This Question
Chromatin Condensation States|DNA Polymerase Directionality|tRNA Charging Accuracy
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Differentiating the specific energy currency (ATP vs.
GTP) used in various stages of translation.
A common misconception is treating all translational energy requirements as identical; however, NCERT specifically highlights ATP for amino acid activation (tRNA charging) and GTP for initiation, translocation, and termination.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Cell – The Unit of Life - Class 11 |
| Concept | Chromatin Condensation States |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |