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Question #46764
The Question
In a patient suffering from a rare ciliopathy, a mutation disrupts the structural integrity of the basal bodies in the polarized epithelial cells of a secretory gland. Beyond the obvious loss of ciliary function, which of the following cellular processes will be most directly compromised as a secondary consequence of this dysfunction?
Options
- A.
Synthesis of glycoproteins and glycolipids within the Golgi cisternae.
- B.
Targeted intracellular transport of Golgi-derived secretory vesicles to the apical membrane.
- C.
Formation of the 9+2 microtubule organization within the basal body structure.
- D.
Generation of ATP by mitochondria required to power the ciliary dynein arms.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Cilia and Flagella Ultrastructure|Golgi Polarity|Glandular Secretion Mechanism
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often compartmentalize organelle functions (Basal body = Cilia; Golgi = Secretion) without realizing their cytoskeletal interdependence.
The basal body acts as the MTOC, organizing the microtubule tracks essential for Golgi-directed apical secretion.
Additionally, Option C exploits a common NCERT quantitative trap by swapping the 9+0 basal body arrangement with the 9+2 axonemal arrangement.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Cell – The Unit of Life - Class 11 |
| Concept | Cilia and Flagella Ultrastructure |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |