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Question #46759
The Question
The dynamic instability of microtubules is crucial for intracellular transport and cellular remodeling. Taxol, a drug that hyper-stabilizes microtubules and prevents their depolymerization, is applied to a testicular tissue culture. While it arrests dividing germ cells, it also severely disrupts the function of the non-dividing sustentacular (Sertoli) cells. Which of the following is the most direct consequence of this cytoskeletal freeze specifically within the Sertoli cells?
Options
- A.
Failure of primary spermatocytes to complete the first meiotic division
- B.
Inability to release mature spermatozoa into the seminiferous tubule lumen (Spermiation)
- C.
Cessation of testosterone synthesis due to blocked cholesterol transport
- D.
Prevention of Follicle Stimulating Hormone (FSH) binding to its membrane receptors
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Comparative_Analysis
Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.
Concepts Behind This Question
Microtubule Dynamic Instability|Sertoli Cell Functions|Adrenal Cortex vs Medulla
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often associate microtubules exclusively with spindle fibers during cell division (mitosis/meiosis).
The trap is failing to recognize their critical role in intracellular transport and dynamic structural remodeling in non-dividing somatic cells (like Sertoli cells).
The question tests the ability to link a core cytological concept (microtubule dynamic instability) to a specific reproductive physiological event (spermiation) described in NCERT.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Cell – The Unit of Life - Class 11 |
| Concept | Microtubule Dynamic Instability |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |