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Question #46749
The Question
A male patient presents with severe chronic muscle fatigue, elevated blood lactate levels, and localized tissue necrosis. Cellular analysis reveals a mutation in a circular, double-stranded DNA molecule that is not associated with histone proteins. Which of the following statements regarding the inheritance and pathophysiology of this condition is INCORRECT?
Options
- A.
The patient inherited this genetic defect exclusively from the cytoplasm of the maternal ovum.
- B.
The patient will transmit this mutation to his daughters, but not to his sons.
- C.
The elevated lactate is due to the failure of oxidative phosphorylation, forcing muscles to rely on anaerobic glycolysis.
- D.
The organelle harboring this mutation utilizes 70S ribosomes to synthesize a fraction of its required proteins.
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Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Comparative_Analysis
Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.
Concepts Behind This Question
Mitochondria|Muscle Fatigue Factors|Metabolic Water Formation
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students frequently confuse Mitochondrial (Cytoplasmic) Inheritance with X-linked inheritance.
In X-linked traits, a father passes the affected X chromosome to all his daughters.
However, in mitochondrial inheritance, a father passes the trait to ZERO offspring, as the zygote's cytoplasm (and thus mitochondria) is derived entirely from the maternal ovum.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Cell – The Unit of Life - Class 11 |
| Concept | Mitochondrial Endosymbiotic Evidence |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |