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Question #46706
The Question
In a frog (Rana tigrina), a metabolic shift causes respiratory intermediates to be heavily withdrawn from the amphibolic pathway for anabolic biosynthesis, resulting in a significant drop in cellular ATP flux. What will be the primary downstream effect of this energy disruption on the frog's gastric digestion?
Options
- A.
Inability to maintain the optimal acidic pH required for the autocatalytic activation of pepsinogen.
- B.
Direct allosteric inhibition of pepsin by accumulated biosynthetic intermediates in the gastric lumen.
- C.
Compensatory hypersecretion of HCl by oxyntic cells to maintain enzyme kinetic specificity.
- D.
Failure of enterokinase to cleave the inactive gastric proenzyme into active pepsin.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Frog Digestive Enzyme Specificity|Amphibolic Pathway
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Connecting cellular bioenergetics (amphibolic pathway/ATP flux) to macroscopic physiological processes (gastric digestion via active transport).
Students often compartmentalize physiology and respiration, failing to realize that exocrine secretion (like HCl) is a highly ATP-dependent active transport process that dictates downstream enzyme kinetics.
Option D exploits a 'Functional Overlap' trap by mixing up gastric and intestinal proenzyme activators.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Structural Organisation in Animals - Class 11 |
| Concept | Frog Digestive Enzyme Specificity |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |