Before You Begin
Question #46520
The Question
An individual develops severe asthma-like symptoms upon exposure to pollen from Parthenium, an invasive alien plant species. Which of the following statements regarding the immunological mechanism of this hyper-sensitization is INCORRECT?
Options
- A.
Sensitization occurs when the Fc region of specific IgE antibodies binds to receptors on the surface of mast cells.
- B.
The massive degranulation of mast cells is triggered when the pollen allergen directly binds to the Fc region of the IgE antibodies.
- C.
The allergic manifestation involves the cross-linking of receptor-bound IgE molecules by the pollen antigens at their Fab regions.
- D.
The exaggerated immune response involves the release of preformed mediators like histamine and serotonin from mast cells.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Fc_Region|Mast_Cells|Histamine_Release
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Distinguishing between the structural domains of an antibody (H2L2).
Students often confuse the functions of the Fab (antigen-binding) and Fc (cell-receptor binding) regions.
The trap exploits this by correctly identifying the molecules involved (allergen, IgE, mast cell) but swapping the specific binding domain, testing deep structural comprehension of NCERT's antibody diagram.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Human Health and Disease - Class 12 |
| Concept | Antibody Structure Logic |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |