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Question #46503
The Question
A patient receives a renal allograft and is prescribed Cyclosporin A, a bioactive molecule derived from Trichoderma polysporum. Which of the following statements is INCORRECT regarding the physiological mechanism and immunological effect of this drug?
Options
- A.
It suppresses cell-mediated immunity, which is primarily responsible for the rejection of the transplanted organ.
- B.
It confers passive immunity to the host by neutralizing the foreign HLA antigens present on the transplanted tissue.
- C.
It inhibits the clonal expansion of T-lymphocytes, thereby preventing the formation of immunological memory against the graft.
- D.
It blocks the transition from antigen presentation to the effector phase, creating an artificially induced immunodeficient state.
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Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Active Immunity|Passive Immunity|Cyclosporin A|T-lymphocytes
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often confuse the clinical 'protection' of a transplanted organ with 'passive immunity'.
The trap relies on the misconception that a drug preventing rejection must be neutralizing the foreign antigens directly.
In reality, Cyclosporin A paralyzes the host's own T-cell machinery (immunosuppression) rather than providing pre-formed immune effectors (passive immunity).
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Human Health and Disease - Class 12 |
| Concept | Active vs Passive Immunity |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |