Question #46428

Read the following statements correlating Chemical Evolution with Biotechnology:

I. The Miller-Urey experiment proved that under primitive reducing conditions ($CH_4, NH_3, H_2, H_2O$ at $800^\circ C$), functional and folded polypeptides could be synthesized abiotically. II. The universal nature of the genetic code allows a human structural gene to be translated in a bacterial cell, but it does not guarantee a biologically active complex protein. III. Transgenic animals are utilized to produce complex human therapeutic proteins (e.g., $\alpha$-1-antitrypsin) because they possess the necessary eukaryotic post-translational modification machinery. IV. While modern transgenic expression requires specific regulatory sequences, the abiotic synthesis of amino acids in the Miller-Urey apparatus was directed by primitive ribozymes.

Which of the following options correctly identifies the INCORRECT statements?