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Question #46387

Difficulty: 8/10 | 🟢 Free

The Question

A patient with a neurohypophyseal lesion exhibits massive diuresis, leading to a significant drop in blood volume and systemic hypotension. Urinalysis reveals no glycosuria. Regarding the physiological consequences and compensatory mechanisms in this patient, which of the following statements is INCORRECT?

Options

  • A.

    Aortic and carotid baroreceptors detect the systemic hypotension and send signals that would normally trigger the release of ADH from the posterior pituitary.

  • B.

    A fall in glomerular blood flow activates the juxtaglomerular (JG) cells to release renin, initiating a cascade to restore blood pressure.

  • C.

    The counter-current multiplier ceases to function, causing the medullary interstitium to lose its hyperosmolarity, which directly results in the excretion of hypotonic urine.

  • D.

    The tubular fluid passing through the collecting duct fails to osmotically equilibrate with the hypertonic medullary interstitium due to the absence of ADH-dependent water channels.

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Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Regulatory_Failure

Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.

Concepts Behind This Question

Loop_of_Henle|Vasopressin|Collecting_Duct

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Students often conflate the 'creation' of the medullary osmotic gradient (Counter-Current Multiplier, which is ADH-independent) with the 'utilization' of that gradient (Collecting Duct permeability, which is ADH-dependent).

The trap assumes that the production of dilute urine implies a failure of the Loop of Henle's multiplier system, whereas it is actually a failure of distal facultative reabsorption.

Quick Facts About This Question

Question Information

SubjectBiology
ChapterBody Fluids and Circulation - Class 11
ConceptHypertension vs Hypotension Logic
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree