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Question #46385
The Question
A patient presents with a rare atrial tumor causing constitutive, excessive secretion of Atrial Natriuretic Factor (ANF). Based on the physiological antagonism between ANF and the Renin-Angiotensin mechanism, which of the following best describes the patient's physiological state and the resulting feedback loop?
Options
- A.
Systemic hypotension and increased natriuresis, accompanied by a compensatory elevation in renin release whose hypertensive effects are continuously blunted.
- B.
Systemic hypotension and increased natriuresis, accompanied by a complete suppression of renin release because ANF acts as an absolute check on the JGA.
- C.
Systemic hypertension and decreased diuresis, accompanied by a compensatory suppression of renin release to prevent further blood pressure elevation.
- D.
Systemic hypotension and decreased natriuresis, accompanied by a compensatory elevation in aldosterone secretion that successfully restores blood volume.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
ANF|RAAS_Pathway|Juxtaglomerular_Apparatus
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often memorize the NCERT line that 'ANF acts as a check on the renin-angiotensin mechanism' and might incorrectly assume ANF completely and permanently shuts down renin production (Option B).
However, they fail to synthesize that severe systemic hypotension (a drop in BP) is the primary, overriding trigger for JGA to release renin.
The core concept is the 'feedback conflict' where the body attempts to compensate for hypovolemia via RAAS, but the constitutive ANF renders the compensation futile.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Body Fluids and Circulation - Class 11 |
| Concept | Hypertension vs Hypotension Logic |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |