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Question #46312
The Question
In an actively contracting skeletal muscle, the local temperature is experimentally maintained at normal resting levels (37°C) despite high metabolic activity. The local pCO2 and H+ concentrations rise normally. Assuming systemic cardiac output is constant, how will this thermal constraint affect the oxygen-hemoglobin dissociation dynamics?
Options
- A.
The rightward shift of the dissociation curve is attenuated, resulting in a lower P50 value compared to a normally exercising muscle, which decreases oxygen unloading.
- B.
The dissociation curve shifts further to the right due to the uncompensated action of high pCO2, increasing oxygen delivery.
- C.
The curve shifts to the left of the normal resting curve, completely inhibiting the Bohr effect.
- D.
The P50 value remains identical to a normally exercising muscle because pCO2 and H+ are the sole regulators of oxygen dissociation.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Hb_Dissociation|Heat_Shock_Thermal_Gradient|Metabolic_Flux
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often memorize the Bohr effect (pCO2 and H+) but neglect the thermodynamic component (temperature) explicitly mentioned in NCERT.
The trap tests the quantitative nuance of P50—understanding that a 'blunted right shift' means a relatively lower P50 and higher O2 affinity, which paradoxically starves the active tissue of oxygen despite high blood flow and high pCO2.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Breathing and Exchange of Gases - Class 11 |
| Concept | Oxygen-Hemoglobin Dissociation Curve |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |