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Question #46204
The Question
During the embryonic development of a vertebrate, a targeted mutation disrupts the formation of adhering junctions in the dorsal ectoderm. However, the mesodermally derived notochord remains structurally and functionally intact. Which of the following represents the most likely developmental outcome?
Options
- A.
The notochord will fail to release inductive morphogens, completely arresting neural development.
- B.
The neural plate will be specified, but the failure of apical constriction will prevent its folding into a neural tube.
- C.
The ectodermal cells will lose their resting membrane potential, preventing the formation of the neural crest.
- D.
The neural tube will invaginate prematurely due to the lack of cementing between neighboring ectodermal cells.
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Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Notochord|Tight_Junctions|Germ_Layer_Induction
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often assume that chemical induction (morphogens from the notochord) is the sole requirement for organogenesis, ignoring the mechanical and structural prerequisites (epithelial junctions) required for tissue morphogenesis.
This question tests the synthesis of 'Structural Organisation in Animals' (cell junctions) with developmental biology principles implied in 'Animal Kingdom' and 'Human Reproduction'.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Animal Kingdom - Class 11 |
| Concept | Evolutionary Notochord Progression |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |