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Question #46183

Difficulty: 8/10 | 🟢 Free

The Question

An amphibian's integument is severely obstructed by an impermeable environmental pollutant, halting cutaneous gas exchange. Given that cutaneous respiration is a major route for CO2CO_2 elimination in these organisms, which of the following physiological cascades will most likely occur in its systemic capillaries?

Options

  • A.

    Increased diffusion of CO2CO_2 into RBCs drives carbonic anhydrase activity forward, leading to an enhanced influx of Cl−Cl^- into RBCs and a rightward shift of the oxygen dissociation curve.

  • B.

    Accumulation of CO2CO_2 in the plasma inhibits carbonic anhydrase, causing an efflux of Cl−Cl^- from the RBCs to maintain electrical neutrality, leading to respiratory alkalosis.

  • C.

    The resulting hypercapnia decreases the formation of HCO3−HCO_3^-, forcing Cl−Cl^- out of the erythrocytes (reverse Hamburger phenomenon) to buffer the plasma pH.

  • D.

    Elevated plasma pCO2pCO_2 directly binds to plasma proteins, reducing the need for the chloride shift and causing a leftward shift of the oxygen dissociation curve.

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Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Regulatory_Failure

Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.

Concepts Behind This Question

Amphibian Integument | Chloride Shift (Hamburger Phenomenon) | Metabolic Flux and Steady State

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Integrating the Hamburger Phenomenon with the Bohr effect under pathological conditions.

Students often memorize the Chloride Shift but fail to apply Le Chatelier's principle to the Carbonic Anhydrase reaction during hypercapnia.

The trap tests the exact direction of Cl−Cl^- movement (influx vs efflux) and the subsequent shift in the oxygen dissociation curve.

Quick Facts About This Question

Question Information

SubjectBiology
ChapterAnimal Kingdom - Class 11
ConceptAmphibian Integument
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree
Animal Kingdom - Class 11 Practice Question 46183 | RankRise360