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Question #45818

Difficulty: 8/10 | 🟢 Free

The Question

In a diploid organism, genes A, B, and C are located on the same chromosome. The genetic map distance between A and B is 20 cM, and between B and C is 40 cM. The physical distance between A and C is 60 cM. Which of the following statements is correct regarding the inheritance of genes A and C?

Options

  • A.

    The observed recombination frequency between A and C will be 60%, indicating they belong to different linkage groups.

  • B.

    Genes A and C will show a maximum recombination frequency of 50% and assort independently, despite being in the same physical linkage group.

  • C.

    The recombination frequency between A and C will be exactly 20% due to complete interference by the intermediate gene B.

  • D.

    Genes A and C will not undergo independent assortment because the principle of independent assortment strictly applies only to genes on non-homologous chromosomes.

Check Your Answer

Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Regulatory_Failure

Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.

Concepts Behind This Question

Linkage Group Calculation|Recombination Frequency (RF)|Chromosomal Theory of Inheritance

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Students often conflate 'physical linkage' (being on the same chromosome) with 'statistical linkage' (RF < 50%).

The common misconception is that genes on the same chromosome can never assort independently, and that map distance directly equals RF even beyond 50 cM.

This question tests the threshold dynamics where multiple crossovers mask linkage.

Quick Facts About This Question

Question Information

SubjectBiology
ChapterPrinciples of Inheritance and Variation - Class 12
ConceptLinkage Group Calculation
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree