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Question #45736
The Question
A patient presents with chronic hypertension and hypervolemia. Investigations reveal normal secretion of Atrial Natriuretic Factor (ANF) in response to increased venous return, but a genetic mutation in the target cells' transmembrane receptors prevents the generation of the secondary messenger (cGMP). Which of the following represents the most likely physiological consequence in this patient?
Options
- A.
Persistent vasodilation of peripheral blood vessels due to the accumulation of circulating ANF.
- B.
Unopposed action of the Renin-Angiotensin-Aldosterone System (RAAS) leading to continuous renal reabsorption of Na⁺.
- C.
Increased release of renin from the Juxtaglomerular apparatus due to the direct stimulatory effect of high blood pressure.
- D.
Enhanced excretion of sodium and water in the urine due to a compensatory increase in Aldosterone secretion.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
ANF|Secondary_Messenger_Cascade|Guanylyl_Cyclase
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Hormone resistance syndrome.
Students often assume high hormone levels automatically lead to their physiological effects.
Here, they must synthesize the mechanism of hormone action (membrane receptors/secondary messengers) with excretory physiology (ANF antagonizing RAAS).
The trap lies in confusing the compensatory responses and the specific actions of Aldosterone vs ANF.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Excretory Products and Their Elimination - Class 11 |
| Concept | ANF Antagonism |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |