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Question #45578
The Question
Certain sexually transmitted infections (STIs) can induce severe placental inflammation, disrupting the endocrine profile of the developing trophoblast. If this inflammation specifically impairs the synthesis of Human Chorionic Gonadotropin (hCG) during the first trimester, what will be the immediate downstream physiological consequence leading to spontaneous abortion?
Options
- A.
Premature degeneration of the corpus luteum, leading to a precipitous drop in ovarian progesterone secretion.
- B.
Direct necrosis of the endometrial stratum functionalis due to the sudden withdrawal of human placental lactogen (hPL).
- C.
Upregulation of maternal oxytocin receptors in the myometrium, triggering immediate parturition reflexes.
- D.
Failure of the maternal anterior pituitary to secrete Luteinizing Hormone (LH), resulting in endometrial sloughing.
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Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
STI_vs_STD_Distinction|Placental_Endocrine_Profile|Corpus_Luteum_Fate
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often memorize that 'STIs cause abortions' (Reproductive Health) and 'hCG maintains the corpus luteum' (Human Reproduction) but fail to synthesize the two.
The trap lies in confusing the source of pregnancy-maintaining hormones in the first trimester (ovarian corpus luteum vs. placenta) and misunderstanding that maternal LH is inactive during this phase, making hCG the sole luteotropic factor.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Reproductive Health - Class 12 |
| Concept | STI vs STD Distinction |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |