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Question #45567
The Question
A female patient living in a tropical ecotone—a region characterized by a high 'edge effect' of opportunistic pathogens—develops chronic pelvic inflammation. This infection leads to the complete destruction of the ciliated epithelium in her fallopian tubes. Clinical evaluation reveals she cannot produce viable ova, but her uterine environment is normal and receptive. Which of the following Assisted Reproductive Technologies (ART) is strictly contraindicated for her, and what is the precise physiological reason?
Options
- A.
GIFT; because the absence of tubal ciliary movement will prevent the transport of the in vivo formed zygote to the uterus, risking ectopic pregnancy.
- B.
ZIFT; because the transferred zygote requires the tubal ampulla to undergo fertilization before moving to the uterus.
- C.
IVF followed by IUT; because the lack of tubal secretions will prevent the cleavage of the embryo inside the uterus.
- D.
GIFT; because the procedure strictly requires the female to produce her own viable ova to interact with the donor sperm in the fallopian tube.
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Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Evolutionary_Exception
Tackle problems where standard rules evolve or change based on specific environmental constraints.
Concepts Behind This Question
GIFT|Ecotone|Fallopian Tube Mucosa
Why This Question Is Tricky
Common Mistakes
The Conceptual Pivot lies in the incomplete memorization of NCERT lines.
Students often memorize that GIFT is for females who 'cannot produce an ovum but can provide a suitable environment', but fail to synthesize that this 'suitable environment' anatomically mandates a functional, ciliated fallopian tube for zygote transport.
Furthermore, the question integrates ecological concepts (ecotone/edge effect) as the etiology of the physiological dysfunction, testing the student's ability to link environmental biology with human reproductive pathology.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Reproductive Health - Class 12 |
| Concept | GIFT Applicability |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |