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Question #45563
The Question
A female patient with a genetic deficiency of a biological product conventionally used to treat emphysema undergoes Intra Uterine Transfer (IUT). Despite the successful transfer of a 16-celled embryo, implantation repeatedly fails due to severe localized uterine inflammation and tissue degradation. Which of the following best explains the molecular basis of this failure?
Options
- A.
The deficient protein acts as a protease inhibitor; its absence causes unchecked proteolysis of the endometrial extracellular matrix, preventing blastocyst adhesion.
- B.
The deficient protein is a pulmonary surfactant; its systemic absence alters the oxygen gradient in the endometrium, causing embryonic hypoxia.
- C.
The deficient protein regulates alpha-lactalbumin synthesis; its absence deprives the blastocyst of essential nutrients required for trophoblast invasion.
- D.
The deficient protein directly suppresses cell-mediated immunity; its absence leads to the activation of maternal T-cells against the zona pellucida.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
IUT|Alpha-1 Antitrypsin|Autoimmunity Principles
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Integrating Biotechnology (AAT's role in emphysema) with Human Reproduction (the mechanics of implantation).
The trap relies on students memorizing 'AAT = Emphysema' without understanding its core biochemical mechanism (protease inhibition) and how that mechanism applies systemically to tissue remodeling events like embryo implantation.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Reproductive Health - Class 12 |
| Concept | ZIFT vs IUT |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |