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Question #45562
The Question
A couple is diagnosed with male factor infertility where the sperm exhibit normal count and motility but completely lack functional acrosomal enzymes. The clinician rejects standard IVF followed by ZIFT (Zygote Intra-Fallopian Transfer) as a treatment plan. What is the precise biological rationale for this rejection, and what is the correct ART alternative?
Options
- A.
Standard IVF fails because sperm cannot digest the zona pellucida to achieve fertilization; ICSI is required to directly inject the sperm into the ovum.
- B.
ZIFT involves the transfer of unfertilized gametes into the fallopian tube where fertilization will fail; GIFT is required to bypass the zona pellucida.
- C.
Standard IVF succeeds, but the resulting zygote lacks the enzymes necessary for cleavage; IUT (Intra-Uterine Transfer) of a blastocyst is required.
- D.
Acrosomal deficiency prevents the sperm from undergoing capacitation in the female reproductive tract during ZIFT; Artificial Insemination (AI) is required.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
ZIFT|IUT|Acrosomal Enzyme Activation
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Distinguishing between the prerequisites of ART procedures.
Students often memorize ART acronyms without linking them to the cellular prerequisites.
The trap relies on confusing the stage of transfer (ZIFT vs GIFT) and misunderstanding that standard IVF still requires the sperm to independently penetrate the ovum, whereas ICSI mechanically bypasses this requirement.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Reproductive Health - Class 12 |
| Concept | ZIFT vs IUT |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |