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Question #45528
The Question
'Saheli', a non-steroidal oral contraceptive pill, prevents pregnancy primarily by altering the receptivity of the endometrium. Based on the principles of chemical coordination, which of the following best describes its molecular mechanism of action?
Options
- A.
It acts as a competitive antagonist at intracellular estrogen receptors, inhibiting the genomic expression required for endometrial proliferation.
- B.
It binds to membrane-bound estrogen receptors, preventing the generation of secondary messengers like cAMP needed for endometrial thickening.
- C.
It acts as a potent agonist at nuclear progesterone receptors, directly inducing a hostile cervical mucus barrier to prevent sperm entry.
- D.
It provides a continuous non-steroidal signal that exerts negative feedback on the hypothalamus, preventing the LH surge and ovulation.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Estrogen Receptor|Transcription Factors|Saheli
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Integrating 'Reproductive Health' (Saheli's function) with 'Chemical Coordination' (Mechanism of steroid hormone action).
The trap relies on students confusing the mechanism of standard steroidal pills (ovulation inhibition) with Saheli (implantation failure via nuclear receptor antagonism), or forgetting that estrogen receptors are intracellular.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Reproductive Health - Class 12 |
| Concept | Saheli Pill Mechanism |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |