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Question #45513
The Question
In an experimental mammalian model, a micro-surgical lesion completely severs the hypothalamo-hypophyseal portal blood vessels, while the neural tracts to the pars nervosa remain intact. Which of the following will be the most direct consequence on the reproductive physiology of the female?
Options
- A.
Arrest of folliculogenesis prior to the formation of the Graafian follicle due to a lack of FSH, resulting in low serum estrogen.
- B.
Continuous development of tertiary follicles, but failure of ovulation due to the absence of an LH surge.
- C.
Hypersecretion of gonadotropins from the pars distalis due to the loss of negative feedback from ovarian inhibin.
- D.
Failure of the corpus luteum to secrete progesterone due to the inability of the hypothalamus to transport oxytocin.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
FSH|LH|Hypothalamo-Hypophyseal Portal System|Ovarian Follicle Stages
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Distinguishing between the vascular (portal) connection of the anterior pituitary and the neural connection of the posterior pituitary.
Students must synthesize this anatomical fact with the endocrine cascade of the menstrual cycle: Hypothalamus (GnRH) -> Portal System -> Anterior Pituitary (FSH/LH) -> Ovary (Folliculogenesis & Estrogen).
Severing the portal system creates a hormonal blockade, leading to secondary hypogonadism and a failure of the estrogen feedback loop.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Human Reproduction - Class 12 |
| Concept | Ovarian Follicle Stages |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |