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Question #45471
The Question
A 26-year-old female is prescribed the non-steroidal oral contraceptive pill 'Saheli'. Unlike standard combined oral contraceptive pills, she continues to experience normal follicular development and ovulation. Which of the following accurately explains the molecular mechanism of this pill and its direct physiological consequence?
Options
- A.
It acts as an estrogen antagonist in the endometrium, preventing the estrogen-mediated upregulation of progesterone receptors and thereby inhibiting implantation.
- B.
It exerts continuous negative feedback on the hypothalamus and anterior pituitary, suppressing the LH surge and preventing the formation of the corpus luteum.
- C.
It competitively binds to progesterone receptors in the endometrium, inducing premature shedding of the uterine lining even if fertilization occurs.
- D.
It directly inhibits the syncytiotrophoblast from secreting hCG, causing the rapid degeneration of the corpus luteum and preventing pregnancy maintenance.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
hCG|Progesterone|Syncytiotrophoblast|Estrogen_Receptor_Antagonist
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often incorrectly assume all oral contraceptive pills work by inhibiting ovulation via negative feedback on the HPG axis.
The critical distinction here is that Saheli is non-steroidal and does not disrupt ovulation.
Instead, it targets the pre-implantation 'nidus' (endometrium) by acting as a SERM, specifically antagonizing estrogen to prevent the necessary endometrial preparation for implantation.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Chemical Coordination and Integration - Class 11 |
| Concept | Progesterone/Estrogen Feedback |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |