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Question #45456

Difficulty: 8/10 | 🟢 Free

The Question

In terrestrial mammals, Atrial Natriuretic Factor (ANF) acts as a crucial vasodilator and natriuretic agent. If mammalian ANF is experimentally administered to a freshwater teleost, it fails to produce a comparable massive sodium-wasting effect. Based on the evolutionary divergence of osmoregulatory mechanisms, which of the following best explains this observation?

Options

  • A.

    Terrestrial mammals evolved ANF as a specific physiological antagonist to the robust RAAS required for land survival, whereas freshwater teleosts rely primarily on gill-based ionocytes and lack this specific RAAS-ANF antagonistic axis.

  • B.

    Freshwater teleosts possess a hyperactive RAAS to excrete excess water, which competitively overrides the vasodilatory and natriuretic effects of the administered mammalian ANF.

  • C.

    The two-chambered heart of teleosts lacks the specific atrial receptors required for ANF binding, as endocrine cardiac tissue is an exclusive evolutionary feature of tetrapods.

  • D.

    ANF acts as a potent vasoconstrictor in aquatic environments to decrease the Glomerular Filtration Rate (GFR), thereby preventing the loss of essential electrolytes.

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Step-by-Step Solution

Explanation

How the Examiner Thinks

Evolutionary_Exception

Tackle problems where standard rules evolve or change based on specific environmental constraints.

Concepts Behind This Question

Evolutionary Chronology|Natural Selection Directionality|ANF

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Students often memorize 'ANF decreases BP' without understanding its evolutionary context as a specific antagonist to RAAS (a terrestrial adaptation).

The trap lies in failing to distinguish between mammalian renal-based osmoregulation (RAAS/ANF) and aquatic gill-based osmoregulation, leading to functional confusion about how these hormones operate across different taxa.

Quick Facts About This Question

Question Information

SubjectBiology
ChapterChemical Coordination and Integration - Class 11
ConceptAtrial Natriuretic Factor (ANF)
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree