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Question #45404
The Question
Read the following statements regarding the hormonal control and stem cell dynamics of human gametogenesis:
I. In females, disrupted FSH receptor signaling during fetal development arrests the mitotic proliferation of oogonia, leading to an absent ovarian reserve. II. In males, spermatogonial stem cells maintain a continuous mitotically active pool post-puberty, making them less vulnerable to embryonic developmental failures than oogonia. III. The primary oocytes within primordial follicles are temporarily arrested in Prophase-I of meiosis and are independent of gonadotropin signaling for their initial formation. IV. A failure in LH receptor signaling in Leydig cells directly halts the mitotic division of primary spermatocytes.
Which of the above statements are CORRECT?
Options
- A.
II and III only
- B.
I, II, and III
- C.
I and IV only
- D.
III and IV only
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Comparative_Analysis
Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.
Concepts Behind This Question
Stem Cells|Ovarian Follicle Stages|Hormone Receptors
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: The fundamental distinction between the timing of mitotic proliferation in male vs. female gametogenesis, and the precise cellular targets of gonadotropins.
Common Misconception: Students often assume FSH is required for the 'formation' of primary oocytes (it is only required for their later follicular maturation) and frequently fall for the terminology trap of 'mitosis' vs 'meiosis' when reading about primary spermatocytes.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Human Reproduction - Class 12 |
| Concept | Differentiation of Stem Cells |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |