Before You Begin
Question #45400
The Question
During the transit of spermatozoa through the epididymis, they undergo crucial biochemical maturation. If a pharmacological agent specifically blocks the cAMP-dependent protein kinase A (PKA) cascade during this epididymal transit, which of the following will be the most likely consequence following ejaculation?
Options
- A.
The spermatozoa will fail to undergo spermiation and remain attached to the Sertoli cells.
- B.
The spermatozoa will undergo premature capacitation and acrosome reaction within the vas deferens.
- C.
The spermatozoa will fail to undergo hyperactivation and capacitation in the female reproductive tract.
- D.
The spermatozoa will be unable to complete the second meiotic division to become haploid.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Sperm Capacitation Location|Spermatogenesis vs. Oogenesis Chronology|Secondary Messenger Cascade
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often isolate facts, memorizing 'capacitation occurs in the female tract' without linking it to the prerequisite 'maturation in the epididymis'.
This question tests the chronological dependency of these events.
Distractors A and D exploit chronological confusion regarding meiosis and spermiation, which occur before epididymal transit.
Distractor B is a location trap, as capacitation does not occur in the male tract.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Human Reproduction - Class 12 |
| Concept | Sperm Capacitation Location |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |