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Question #45399
The Question
During a standard In-Vitro Fertilization (IVF) procedure, freshly collected human sperm are immediately co-incubated with a retrieved secondary oocyte in a basic nutrient medium that completely lacks calcium ionophores or any capacitation-inducing factors. Which of the following accurately describes the immediate physiological outcome and its consequence on the planned Artificial Reproductive Technology (ART)?
Options
- A.
Sperm will penetrate the zona pellucida but fail to induce the cortical reaction, leading to polyspermy and the subsequent failure of Intra Uterine Transfer (IUT).
- B.
Sperm will fail to undergo the acrosome reaction at the zona pellucida, preventing syngamy and rendering Zygote Intrafallopian Transfer (ZIFT) impossible.
- C.
Syngamy will occur normally, but the resulting embryo will arrest at the 8-blastomere stage, necessitating IUT instead of ZIFT.
- D.
Capacitation will occur spontaneously, but the absence of female reproductive tract secretions will prevent cleavage, halting the IVF process.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Comparative_Analysis
Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.
Concepts Behind This Question
Sperm Capacitation Location|ZIFT vs IUT|Implantation and Syncytiotrophoblast
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often memorize ART acronyms (ZIFT, IUT, IVF) without connecting them to the prerequisite cellular events.
The trap tests the realization that IVF is not merely 'mixing gametes in a petri dish' but requires simulating the female tract's capacitation environment.
Failing to recognize that capacitation is an absolute prerequisite for the acrosome reaction leads to incorrectly assuming fertilization will still occur.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Human Reproduction - Class 12 |
| Concept | Sperm Capacitation Location |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |