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Question #45286
The Question
A novel chemical inhibitor specifically prevents the formation of recombination nodules during Prophase I of meiosis in a human primary spermatocyte. Which of the following represents the most accurate sequence of cytological and genetic consequences?
Options
- A.
Failure of synapsis during zygotene -> Bivalents fail to form -> Complete arrest of meiotic division.
- B.
Absence of chiasmata formation -> Loss of bivalent tension at Metaphase I -> Chromosomal non-disjunction leading to aneuploidy.
- C.
Inhibition of recombinase enzyme -> Failure of centromere splitting at Anaphase I -> Formation of polyploid gametes.
- D.
Persistence of the synaptonemal complex -> Premature terminalisation of chiasmata -> Random alignment of univalents at Metaphase I.
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Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Regulatory_Failure
Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.
Concepts Behind This Question
Recombination Nodule Function|Chromosomal Theory of Inheritance|Plant Cell Cytokinesis
Why This Question Is Tricky
Common Mistakes
Conceptual Pivot: Students often view recombination nodules solely as agents of genetic variation, missing their structural necessity.
Chiasmata act as mechanical tethers essential for proper bivalent orientation and tension at the Metaphase I plate.
The trap also tests the chronological sequence of Prophase I (Synapsis before Nodules) and the precise definition of Aneuploidy vs.
Polyploidy.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Cell Cycle and Cell Division - Class 11 |
| Concept | Recombination Nodule Function |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |