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Question #45285

Difficulty: 8/10 | 🟢 Free

The Question

In a mutant strain of a diploid organism, a genetic defect completely inhibits the formation of recombination nodules during the pachytene stage of meiosis. If a dihybrid organism (AaBb) with genes A and B located on the same chromosome in a cis arrangement is test-crossed, which of the following represents the correct phenotypic ratio of the progeny and the effective genetic map distance between genes A and B?

Options

  • A.

    1:1:1:1 ; Map distance is 50 cM

  • B.

    1:1 (Parental types only) ; Map distance is 0 cM

  • C.

    9:3:3:1 ; Map distance is proportional to physical distance

  • D.

    1:1 (Parental types only) ; Map distance is equal to their physical distance in base pairs

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Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Comparative_Analysis

Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.

Concepts Behind This Question

Recombination Nodule Function|Linkage Group Calculation|Chromosomal Theory of Inheritance

Why This Question Is Tricky

Common Mistakes

Conceptual Pivot: Distinguishing between physical distance and genetic map distance.

Students often assume physically distant genes must have a map distance > 0.

However, Sturtevant's genetic mapping relies entirely on crossover frequency.

A failure in recombination nodule formation drops the recombination frequency to zero, making the genetic map distance 0 cM and resulting in complete linkage, regardless of the physical base-pair separation.

Quick Facts About This Question

Question Information

SubjectBiology
ChapterCell Cycle and Cell Division - Class 11
ConceptRecombination Nodule Function
Difficulty8
Cognitive Load5
Target Solve Time120 sec
AccessFree