Before You Begin
Question #45189
The Question
Alpha-1 antitrypsin (A1AT) is a crucial biological product. Suppose a widespread genetic mutation in a wild mammalian population leads to a severe A1AT deficiency. Which of the following statements INCORRECTLY correlates the molecular pathology of this defect with its ecological and evolutionary consequences?
Options
- A.
Uninhibited alveolar elastase activity destroys the pulmonary parenchyma, decreasing the respiratory surface area and reducing oxygenation.
- B.
The resulting physiological handicap lowers the population's intrinsic rate of natural increase (r), thereby reducing its Darwinian fitness.
- C.
The population will compensate for the handicap by expanding its fundamental niche, thereby avoiding competitive exclusion and maintaining its ecological fitness.
- D.
Reduced foraging stamina due to poor oxygenation acts as a strong negative selection pressure, potentially altering the population's genetic structure.
Check Your Answer
Correct Answer
Step-by-Step Solution
Explanation
How the Examiner Thinks
Comparative_Analysis
Sharpen your ability to evaluate multiple scenarios and distinguish between competing potential answers.
Concepts Behind This Question
Alpha-1 Antitrypsin|ADA Deficiency Genetic Correction|Gene Therapy Germline vs Somatic
Why This Question Is Tricky
Common Mistakes
The conceptual pivot integrates molecular pathology (Biotechnology/Human Physiology) with population ecology.
The trap relies on the common misconception that organisms can actively 'expand' their fundamental niche to compensate for a genetic handicap.
In reality, a fundamental niche is determined by physiological limits, and a genetic defect like A1AT deficiency strictly reduces Darwinian fitness, making the population vulnerable to competitive exclusion.
Quick Facts About This Question
Question Information
| Subject | Biology |
| Chapter | Biotechnology and Its Applications - Class 12 |
| Concept | Alpha-1 Antitrypsin |
| Difficulty | 8 |
| Cognitive Load | 5 |
| Target Solve Time | 120 sec |
| Access | Free |