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Question #123051

Difficulty: 8/10 | 🟢 Free

The Question

Given below are two statements: an Assertion (A) and a Reason (R).

Assertion (A): Pharmacological inhibition of the chloride shift (Hamburger phenomenon) in erythrocytes will eventually lead to a compensatory decrease in the available Inspiratory Reserve Volume (IRV). Reason (R): Blockage of HCO3- efflux causes product inhibition of carbonic anhydrase, leading to systemic hypercapnia which stimulates the chemosensitive area to increase Tidal Volume (TV).

Select the most appropriate option:

Options

A.
Both (A) and (R) are correct and (R) is the correct explanation of (A).
B.
Both (A) and (R) are correct but (R) is not the correct explanation of (A).
C.
(A) is correct but (R) is not correct.
D.
(A) is not correct but (R) is correct.

Check Your Answer

Correct Answer

Step-by-Step Solution

Explanation

How the Examiner Thinks

Regulatory_Failure

Understand how NOT, EXCEPT, and logical constraints are used to manipulate exam results.

Concepts Behind This Question

Tidal Volume|Residual Volume|Carbonic Anhydrase

Why This Question Is Tricky

Examiner Levers

Pattern Traps

Forces student to avoid "obvious" but wrong patterns or sequences.

Difficulty Boost : +2

Logical Assertion

Tests the causal relationship between two true statements.

Difficulty Boost : +4

Common Mistakes

Conceptual Pivot: Integrating biochemical gas transport with mechanical respiratory volumes.

Students often memorize respiratory volumes as static, isolated numbers (e.g., TV = 500 mL, IRV = 2500-3000 mL) without realizing they are dynamic functional spaces.

If resting TV increases due to hypercapnia-induced hyperventilation, the remaining 'reserve' (IRV) must proportionally decrease.

Furthermore, it tests the biochemical consequence of halting the chloride shift (product inhibition of carbonic anhydrase).

Quick Facts About This Question

Question Information

Subject	Biology
Chapter	Breathing and Exchange of Gases - Class 11
Concept	Respiratory Volume vs. Capacity
Difficulty	8
Cognitive Load	6
Target Solve Time	140 sec
Access	Free